Setfx is a selected combination of fungi, bacteria and microorganisms that have been tested to colonize within potatoes and enhance tuber set and size. It enhances the plants ability to metabolize nutrients to efficiently support growth. Setfx can be applied at three different timings to influence production. Applied to the seed potatoes, Setfx promotes root and stolon development prior to vegetative growth, leading to a dominant potato set and uniform size. Applied in furrow, Setfx increases overall yield by influencing size and number of potatoes of each set. Applied to foliage in early development it increases overall yield. Some benefits include: phosphate solubilization through microbial activity, increased total leaf area, reduced ethylene production (associated with aging and senescence), pH regulation, reduced reactive oxygen species, general stress mitigation, better stems and increased yield.